Week 4 Predictions

New York Giants (1-2) vs Washington Redskins (1-2)

The Giants come in off a win while the Redskins come in off a loss. Giants QB Eli Manning completed 21-of-28 passes for 234 yards, two touchdowns, and zero interceptions in the Giants' Week 3, 30-17 win over the Texans, but the Giants have the 22nd ranked defense. Redskins QB Kirk Cousins completed 30-of-48 passes for 427 yards with three touchdowns and one interception in Sunday's Week 3 loss at Philadelphia. Redskins defense is ranked 4th but the Giants have won the last two matchups. Prediction: Giants

Green Bay Packers (1-2) vs Chicago Bears (2-1)

Packers come in off a loss while Bears come in off a win. Packers QB Aaron Rodgers completed 16-of-27 passes for 162 yards, one touchdown and zero interceptions in the Packers' 19-7, Week 3 loss to the Lions. Packers have the 20th ranked defense. Bears QB Jay Cutler completed 23-of-38 passes for 225 yards and two touchdowns in the Bears' Week 3, 27-19 win over the Jets on Monday night. Bears have the 23rd ranked defense. Prediction: Packers

Tennessee Titans (1-2) vs Indianapolis Colts (1-2)

Titans come in off a loss while Colts come in off a win. Titans QB Jake Locker completed just 17-of-34 passes for 185 yards, zero touchdowns, and two interceptions in the Titans' Week 3, 33-7 blowout loss to the Bengals. Titans have the 5th ranked defense. Colts QB Andrew Luck completed 31-of-39 passes for 370 yards, four touchdowns, and no turnovers in Sunday's Week 3 blowout win over the Jaguars. Colts have the 29th ranked defense. Colts have won all three of their last meetings. Prediction: Colts

Miami Dolphins (1-2) vs Oakland Raiders (0-3)

Both teams come in off losses last week. Dolphins QB Ryan Tannehill completed 21-of-43 passes for 205 yards and one touchdown in the Dolphins' Week 3 loss to Kansas City. Dolphins have the 9th ranked defense. Raiders QB Derek Carr completed 21-of-34 passes for 174 yards and an interception in Sunday's Week 3 loss to the Patriots. Raiders have the 12th ranked defense. Dolphins have won all three of their last meetings. Prediction: Dolphins

Detroit Lions (2-1) vs New York Jets (1-2)

Lions come in off a win while Jets come in off a loss. Lions QB Matthew Stafford completed 22-of-34 passes for 246 yards, zero touchdowns and two interceptions and a fumble in the Lions' 19-7 Week 3 win over the Packers. Lions have the number one ranked defense in the league. Jets QB Geno Smith completed 26-of-43 passes for 316 yards, one touchdown, and two interceptions in the Jets' 27-19, Week 3 loss to the Bears on Monday night. Jets have the number 2 ranked defense. Lions won their last matchup. Prediction: Lions

Tampa Bay Buccaneers (0-3) vs Pittsburgh Steelers (2-1)

Bucs come in off a loss while the Steelers come in off a win. Bucs QB Josh McCown left their Thursday night loss with a thumb injury and has not been ruled out for the game. Bucs have the 28th ranked defense. Steelers QB Ben Roethlisberger completed 22-of-30 passes for 196 yards and two touchdowns in Sunday night's 37-19 blowout of the Panthers. Steelers have the 18th ranked defense. Steelers have won all three of the last meetings. Prediction: Steelers

Carolina Panthers (2-1) vs Baltimore Ravens (2-1)

Panthers come in off a loss while Ravens come in off a win. Panthers QB Cam Newton completed 24-of-35 passes for 250 yards and a touchdown in Sunday night's Week 3 loss to the Steelers. Panthers have the 14th ranked defense. Ravens QB Joe Flacco completed 19-of-31 passes for 217 yards, a touchdown, and an interception in the Ravens' Week 3 win over the Browns. Ravens have the 16th ranked defense. Ravens lead the series but Panthers won the last matchup. Prediction: Panthers

Buffalo Bills (2-1) vs Houston Texans (2-1)

Both teams come in off a loss last week. Bills QB E.J. Manuel completed 23-of-39 passes for 238 yards and a touchdown against the Chargers Week 3. Bills have the 15th ranked defense. Texans QB Ryan Fitzpatrick completed 20-of-34 passes for 289 yards, one touchdown, and three interceptions in the Texans' Week 3 loss to the Giants. Texans have the 15th ranked defense. Texans won the last two matchups. Prediction: Bills

Jacksonville Jaguars (0-3) vs San Diego Chargers (2-1)

Jags come in off a loss while the Chargers come in off a win. Jags QB Chad Henne was benched during the halftime of last week's loss and rookie QB Blake Bortles has been named the starter for the rest of the season. Jags have the last ranked defense in the league. Chargers QB Philip Rivers completed 18-of-25 passes for 256 yards and two touchdowns against the Bills. Chargers have the 10th ranked defense. Chargers have won all of the last three matchups. Prediction: Chargers

Atlanta Falcons (2-1) vs Minnesota Vikings (1-2)

Falcons come in off a win while the Vikings come in off a loss. Falcons QB Matt Ryan went 21 for 24 with 286 yards and three touchdown passes in Thursday's blowout win over Tampa Bay. Falcons may have the number one ranked offense but they have the 27th ranked defense overall. Vikings lost starting QB Matt Cassel for the season leaving rookie QB Teddy Bridgewater to make his first NFL start this week. Vikings have the 11th ranked defense. Falcons have won the last two matchups. Prediction: Falcons

Philadelphia Eagles (3-0) vs San Francisco 49ers (1-2)

Eagles come in off a win while the 49ers come in off a loss last week. Eagles QB Nick Foles completed 28-of-42 passes for 325 yards with three touchdowns in Sunday's Week 3 win over the Redskins. Eagles have the 26th ranked defense. 49ers QB Colin Kaepernick completed 29-of-37 passes for 245 yards, one touchdown in San Francisco's 23-14 Week 3 loss to the Cardinals. 49ers have the sixth ranked defense. The teams have split their matchups with 49ers winning the last. Prediction: 49ers

New Orleans Saints (1-2) vs Dallas Cowboys (2-1)

Both teams come in off wins last week. Saints QB Drew Brees completed 27-of-35 passes for 293 yards and two touchdowns in New Orleans' 20-9, Week 3 win over the Vikings. Saints have the 24th ranked defense. Cowboys QB Tony Romo completed 18-of-23 passes for 217 yards, two touchdowns, and an interception in the Cowboys' 34-31 win over the Rams. Cowboys have the 21st ranked defense. Saints have won all three of the last matchups. Prediction: Saints

New England Patriots (2-1) vs Kansas City Chiefs (1-2)

Both teams come in off wins last week. Patriots QB Tom Brady completed 24-of-37 passes for 234 yards and a touchdown in Sunday's Week 3 win over the Raiders. Patriots have the third ranked defense. Chiefs QB Alex Smith completed 19-of-25 passes for 186 yards and three touchdowns in the Chiefs' Week 3 win over the Dolphins. Chiefs have the 19th ranked defense. Pats have won the last two matchups. Prediction: Patriots